ODCs

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3 associated genes
4 signs/symptoms

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
14 signs/symptoms

Well-differentiated liposarcoma

Growth delay due to insulin-like growth factor I resistance


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MDM2	(0.88)	IGF1R

Citations in the biomedical literature:

Well-differentiated liposarcoma		Growth delay due to insulin-like growth factor I resistance
	Synonym(s): - ALT - Atypical lipoma - Atypical lipomatous tumor - WDLS		Synonym(s): - Resistance to IGF-1

	Classification (Orphanet): - Rare oncologic disease		Classification (Orphanet): - Rare endocrine disease - Rare genetic disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Endocrine, nutritional and metabolic diseases -

	Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: adult Type of inheritance: sporadic		Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: no data available Type of inheritance: autosomal dominant

	External references: No OMIM references No MeSH references		External references: 1 OMIM reference - No MeSH references

Well-differentiated liposarcoma		Growth delay due to insulin-like growth factor I resistance
	Very frequent - Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma - Subcutaneous nodules / lipomas / tumefaction / swelling Occasional - Functional anomalies of the kidney and the urinary tract - Intestinal transit disorder		Very frequent - Autosomal dominant inheritance - Autosomal recessive inheritance - Chromosomal or genetic anomaly - Intrauterine growth retardation - Short stature / dwarfism / nanism Frequent - Abnormally placed nipples - Broad nasal root - Everted lower lip - Intellectual deficit / mental / psychomotor retardation / learning disability - Microcephaly - Pectus excavatum - Philtrum flat / large / featureless / absent cupidon bows - Short hand / brachydactyly - Thin / retracted lips